Proteins
(Short Note)
Definition
Proteins are polymers of amino acids
in which different amino acids are linked together through peptide bonds.
Explanation
Proteins consists of one or more polypeptides
chain. In general, protein molecules consist of forty to ten thousands or more
amino acids units.
The word protein is derived from the Greek word Proteins which means first or of primary importance, in fact proteins are the primary materials of life.
Proteins have very high molecular mass, for e.g. the molecular mass of egg albumin is about 43,000 a.m.u and that of serum albumin is 7,000 a.m.u.
The word protein is derived from the Greek word Proteins which means first or of primary importance, in fact proteins are the primary materials of life.
Proteins have very high molecular mass, for e.g. the molecular mass of egg albumin is about 43,000 a.m.u and that of serum albumin is 7,000 a.m.u.
Plants form Proteins from the simple
inorganic substances and phosphates. Animals cannot synthesize proteins from
inorganic substance. Therefore, they depend upon plants and other animals for
dietary Proteins. Animals prepare their own proteins from simple organic
molecules. Proteins are necessary for growth and for maintaining existing
tissues.
Classification of Proteins
Millions of kinds of proteins exist.
The human body may contain as many as five million different kinds of Proteins.
Commonly proteins are classified into
the following three classes.
1. Simple Proteins
2. Conjugated Proteins
3. Derived Proteins
1. Simple Proteins
The Proteins which on hydrolysis gave
only amino acids or their derivatives, are called simple proteins. They are
further classified into following six classes.
a. Albumins
These Proteins are water soluble, and
are coagulated by heat. They may be precipitated by saturating their solution
with Ammonium Sulphate.
For Example, Egg albumin and serum etc.
For Example, Egg albumin and serum etc.
b. Globulins
These Proteins are insoluble in water
but soluble in dilute salt solution and in dilute solution of strong inorganic
acids and basis. They are coagulated by heat.
For Example, Serum Globulins and tissues etc.
For Example, Serum Globulins and tissues etc.
c. Prolamins
These Proteins are insoluble in H2O
or salt solution, but are soluble in dilute acids and alkalis.
For Example, Zein, Gliadin and
Hordein etc.
d. Glutelins
These Proteins are insoluble in water
or dilute salt solution but are soluble in the dilute acids and basis. These
are coagulated by heat.
For Example, Glutelin and Oryzenin etc.
For Example, Glutelin and Oryzenin etc.
e.
Albuminoids
These Proteins are insoluble in water
or salt solution but are soluble in concentrated acids and base.
For example, Keratins and Fibroin
etc.
f. Basic
Protein
These proteins are strong basic.
For example, Keratins and Fibroin
etc.
2. Conjugated Proteins
Those Proteins which contain a non
proteinic group attached to the proteinic group are called conjugated proteins.
The non proteinic group is called Prosthetic group. This group may be separated
from the proteinic part by careful hydrolysis.
Conjugated Proteins are further
divided into the following five groups.
a. Nucleo
Proteins
The prosthetic group is a nucleic
acid. This protein is present in the nuclei of living cell.
b. Chromo
Proteins
These are coloured protein. The
colour is due to the prosthetic group.
c. Glyco
Proteins
In these proteins the prosthetic
group contains a carbohydrate or a derivative of carbohydrate.
d. Lipo Proteins
In these proteins prosthetic group is
a lipid.
e. Phospho
Protein
In these proteins the prosthetic
group contains a phosphoric acid.
3. Derived Proteins
The derived proteins are the
degradation products obtained by the action of acids, bases or enzymes on
proteins. These includes peptones polypeptides and Proteose.
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